Amino Acid Profile
Amino acids and their derivatives are key-role metabolites, as they are the building blocks of proteins and act as precursor compounds for the biosynthesis of neurotransmitters, hormones, phosphoglycerols, glycolipids and nucleic acids. They play a dominant role in energy metabolism, neurotransmission, lipid transport and other important biochemical processes.
Regulations in amino acids can be linked to disturbances in metabolism and in extension to health diseases, malnutrition or other conditions. Deficiencies in many amino acids can affect the reproductive, immune and nervous system, as well as gut function and can occur at any age with higher possibility during infancy and early childhood.
The analysis of amino acids is performed with HILIC-MS/MS (Virgiliou et al.) and the obtained concentrations can be of service in monitoring and evaluating numerous disorders, including neurological and endocrine disorders, nutritional problems, renal and hepatic dysfunction.
Applications
What are the essential amino acids?
Amino acids are organic compounds composed mainly of nitrogen, carbon, hydrogen, and oxygen. Our body needs 20 different amino acids for its proper function and nine are considered essential: lysine, valine, histidine, methionine, isoleucine, leucine, phenylalanine, threonine, and tryptophan. Essential amino acids can only be obtained from diet and are the core of many vital processes.
Available Tests
Amino acid and derivatives analysis in urine
Alanine (Ala) Arginine (Arg)
Asparagine (Asn) Aspartate (Asp) Cystine (Cys) Glutamate (Glu) Glutamine (Gln) Glycine (Gly) Isoleucine (Ile) Leucine (Leu) Lysine (Lys) Methionine (Met) Phenylalanine (Phe) Proline (Pro) Serine (Ser) Tryptophan (Try) Tyrosine (Tyr) Valine (Val) Threonine (Thr)
Method Report
Related Articles
Quantification of endogenous aminoacids and aminoacid derivatives in urine by hydrophilic interaction liquid chromatography tandem mass spectrometry, Virgiliou, C.
Lab Report Writing – an Introduction
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Where can I go to provide a sample for testing?
Our country possesses approximately 170 billion barrels of oil that can be recovered with today’s technology. Of that number, 165 billion barrels are located in the oil sands.
What happens to my sample once I have provided it?
Our country possesses approximately 170 billion barrels of oil that can be recovered with today’s technology. Of that number, 165 billion barrels are located in the oil sands.
How long does testing typically take before results are available?
Our country possesses approximately 170 billion barrels of oil that can be recovered with today’s technology. Of that number, 165 billion barrels are located in the oil sands.
What will laboratory testing cost me?
Our country possesses approximately 170 billion barrels of oil that can be recovered with today’s technology. Of that number, 165 billion barrels are located in the oil sands.