Using Testing Options
Ceramides belong to a large class of bioactive sphingolipids consisting of a long chain sphingosine base and a fatty acid. They are found in both cells and tissues and a plethora of research studies have demonstrated that they are involved in the formation of cell’s membranes, contributing to their structural stability, as well as in various biological processes, such as signal transduction, stress response and apoptosis.
Acylcarnitines are an acetylated form of L-carnitine naturally produced by the human body or obtained through diet. These esters are considered essential for the catabolism of fatty acids and for the maintenance of energy homeostasis in the human body. Acylcarnitines have many important functions including the control of several mitochondrial enzymes activity.
Fatty acids are building blocks of lipids and have many important functions in the body, including energy storage, membrane composition and influence of cell and tissue metabolism, as well as the responsiveness to hormonal and other signals.
Lipidomics describes the various lipid species present in an organism or sample. Lipidomics involves systems-level identification of pathways and networks, interactions with other biomolecules (e.g proteins) and other moieties in vivo.
Metabolomics aims at the analysis of the whole small molecule (metabolite) complement of a sample in order to relate metabolite levels with certain characteristics or properties of the sample.
and numerous other fit for purpose analyses: amines, saccharides, nucleosides. Please enquire for a list.
Overview
Blood is a rich biological sample routinely collected in clinical laboratories for various cases and is widely used for matabolomics-based analyses. Blood metabolic profile provide a holistic “snapshot” of all transformations occurring in a living organism, as it’s an immediate reflection of both exposome and internal perturbations.
Together with urine blood serum and plasma are the most commonly used matrices in metabolomics-based studies.
Why measure in urine?
- Non-invasive sampling
- Easy to collect in large quantities
- Direct and reflection of organism’ metabolic activity
- Longer time frame of metabolic coverage (compared to blood)
Easy and simple way to:
- Monitor your overall health
- Diagnose a medical condition
- Monitor a medical condition
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ThetaBiomarkers’ blood analysis methodologies offer comprehensive analysis of acylcarnitines, ceramides and fatty acids.
Results can be combined with other ThetaBiomarkers’ services for maximal insights. Export data is quantitative, enabling accurate health monitoring and evaluation and nutritional advices.
Analytical methods (UPLC-MS/MS and GC-MS/MS) employ isotopically labeled internal standards and have been fully validated extensively.